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Axsome Therapeutics, Inc. (NASDAQ:AXSM)

US · Delayed Price · Currency is USD
145.04-11.03 (-7.07%)
 
Market Cap7.60B+7.7%
Revenue (ttm)776.57M+56.9%
Net Income-191.64M+22.4%
EPS-3.75+26.0%
Shares Out52.38M
PE Ration/a
Forward PE36.69
Dividendn/a
Ex-Dividend Daten/a
Volume1,593,180
Open154.30
Previous Close156.07
Day's Range143.90 - 154.74
52-Week Range123.50 - 260.19
Beta0.60
AnalystsBuy
Price Target283.00(+95.12%)
Earnings DateNov 2, 2026
Insider Score
––Not scored
AXSM Insider Score

Insiders filed in the last 90 days, but none of those trades qualified for scoring — round-trip buys and filings whose price is far off the market are excluded.

About AXSM

Axsome Therapeutics, Inc. is a biopharmaceutical company dedicated to discovering and advancing innovative treatments for a range of central nervous system (CNS) disorders within the United States. Its robust product pipeline features several promising candidates, including: AXS-05, an investigational therapy currently being developed for major depressive disorder and treatment-resistant depression. This compound is also in Phase III clinical evaluation for Alzheimer's disease agitation and has successfully finished Phase II trials investigating its use for smoking cessation. AXS-07, a novel, orally administered, rapidly-acting investigational medicine that employs multiple mechanisms of action. It has concluded two Phase III studies for the acute treatment of migraine attacks. AXS-12, a selective and potent norepinephrine reuptake inhibitor, which is presently undergoing a Phase III trial for narcolepsy. AXS-14, an oral investigational drug, advancing through Phase III trials for the management of fibromyalgia. Axsome Therapeutics also engages in a research collaboration with Duke University to further assess AXS-05's potential in smoking cessation. The company, established in 2012, has its main offices in New York, New York.

Address
One World Trade Center, New York City, NY, 10007, US
Market Cap
7.60 billion
Employees
1,346
Industrial Classification
Biotechnology

What Are Insiders Doing?

Open-market buy / sell balanceNet Selling
Sold
$50.00M
Bought
$0

View the trades behind this meter — each links to its SEC Form 4 →

Open-market Form 4 purchases (code P) vs sales (code S) on file for this company. Grants, option exercises and tax withholdings are excluded. Informational only.

1 Day
-7.07%
5 Days
-7.93%
1 Month
-25.65%
6 Months
-22.00%
1 Year
+7.69%

$AXSM stock is featured in our Insider Score Rankings, and Insider Trades datasets.

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Recently reported changes in AXSM holdings by institutional investors

Scanning latest 13F filings…

Latest 0 13F filings · Source: SEC EDGAR

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Insider Trading

Quarterly net insider trading by AXSM's directors and management

Net Shares Purchased by Insiders−200k−100k02025Q42026Q12026Q22026Q32026Q4

Source: SEC EDGAR (Form 4)

Corporate Lobbying

AXSM Estimated quarterly lobbying spending

Source: U.S. Senate LDA

AXSM Revenue by Segment or Geography

$220.35MTotal
SegmentRevenue% of All
Product Sales$216.35M98.19%
Royalty and Milestone Revenue$2.02M0.92%
Royalty Revenue$1.47M0.67%
Milestone Revenue$500.00K0.23%

As of: Q2 2026 (Jun 30, 2026) · Source: SEC EDGAR (10-Q)

U.S. Patents

New AXSM patent grants

Loading patent grants…

Source: USPTO Open Data Portal

Government Contracts

Estimated quarterly amount awarded to AXSM from public contracts

Source: USAspending.gov

Top ETF Holders

ETFs with the largest estimated holdings in AXSM

ETFEst. Holding Size
VTIVanguard Morningstar Total Stock Market ETF$261.60M
VBVanguard Morningstar Small-Cap ETF$184.71M
VBKVanguard Morningstar Small-Cap Growth ETF$102.71M
VXFVanguard Extended Market ETF$92.57M
FBTFirst Trust NYSE Arca Biotechnology Index Fund$84.36M
IBBiShares Biotechnology ETF$52.46M

Estimated from each fund’s disclosed top holdings × AUM

AXSM Insider Score

Our composite score: insider buying, sector, volume, tone & dilution

Members only

The live Insider Score for AXSM is included with Insider Access.

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Bull Case vs Bear Case

AI-generated from AXSM’s recent data — informational, not investment advice

Generating analysis…

Insider Score

Our 0–100 Insider Score and the signals behind it.

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Recent Insider Activity

Buys
0
Sells
16
Buy Value
$0
Distinct Buyers
0

Frequently Asked Questions

Disclaimer — Informational only — not investment advice. Insider transaction data is sourced from SEC Form 4 filings; market data from public feeds and may be delayed. The Insider Score is a proprietary score for research purposes and does not predict future performance. Always do your own research.